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The lateral meningocele syndrome mutation causes marked osteopenia in mice

Disturbances in the endoplasmic reticulum can be triggered by increased oxidative stress, deposition of saturated fatty acids, hypoxia, or other stimuli, which in turn cause the accumulation of unfolded proteins in the endoplasmic reticulum lumen that is filled with proteins, antioxidants, or essential metals

Suitable for All Lifestyles: Students : Ideal for managing tension from long study hours and prolonged postures in front of books or computers

Rats weighing 250300 g were purchased from Harlan Laboratories and were maintained on a normal day/night cycle at 21C with ad libitum access to food and water