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Use caution in patients with liver disease [see Warnings and Precautions (5.4)]
The study demonstrated that in spontaneously hypertensive rats, liraglutide reduced circulating Ang II levels, upregulated cardiac angiotensin II type 2 receptor (AT2R) and angiotensin-converting enzyme-2 (ACE2) expression, and attenuated myocardial hypertrophy [145]
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