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Based on these results, we proposed a Funnel model incorporating both assays for efficient early-stage screening of BBB-permeable compounds (Figure 4)
Within the Vitamin B complex, there are several members, including Vitamin B1 (thiamine), Vitamin B2 (riboflavin), Vitamin B3 (niacin), Vitamin B5 (pantothenic acid), Vitamin B6 (pyridoxine), Vitamin B7 (biotin), Vitamin B9 (folate), and notably, vitamin B12 (cobalamin)
Unlike its naturally derived precursor, Epithalon is a single, precise molecular entity (Ala-Glu-Asp-Gly)
Majumder et al., 2013)
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