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Clinical weight-loss protocols do not escalate semaglutide beyond 2.4 mg weekly, as this is the maximum therapeutic dose validated in trials
Because sustainable weight loss typically occurs gradually, peptide-supported programs often focus on steady progress rather than rapid weight reduction
Individual results vary significantly, and factors like starting weight, diet, exercise, and genetics all influence outcomes
These AISRS thresholds offer an alternative to the clinical global impression (CGI)based threshold of 18, which is not aligned with ADHD clinical practice
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