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The Neh2 domain is a regulatory domain containing the DLG and ETGE binding motifs, through which NRF2 interacts with its major negative regulator, KEAP1, and is essential for the KEAP1-mediated degradation of the protein by the proteasome [128, 143,144,145]

H., & Park, H

Because the way it works at the surface level is genuinely useful

PS-MPs exposure could affect the ER stress of ovarian cells The analysis of ovarian RNA-seq data revealed that Hspa1a was enriched in several KEGG signaling pathways, including protein processing in the ER, antigen processing and presentation, estrogen signaling pathways, endocytosis, and MAPK signaling pathways