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Practical differences come down to insurance coverage, cost, and availability
Nabeno M, Akahoshi F, Kishida H, Miyaguchi I, Tanaka Y, Ishii S, et al
A recent real-world study from Virta Health found that individuals with type 2 diabetes who discontinued GLP-1 therapy while continuing a ketogenic or low-carb diet maintained their weight loss over 12 months, with more than 70% sustaining at least 5% weight loss
When these medications slow that process, the effects are widespread: food moves more slowly, nutrient absorption patterns change, and the feedback loops between gut and brain are recalibrated
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