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In 1967 Steiner showed that insulin was synthesised from a precursor protein, called proinsulin
doi:10.1007/s00125-010-2028-x 263
The study, Cutaneous Adverse Events Associated With GLP-1 Receptor Agonists: A FAERS Database Analysis From 2018-2024, looked at data from the FDA Adverse Event Reporting System on the following GLP-1 agonists: semaglutide, liraglutide, exenatide, and dulaglutide
Other side effects can occur, but they are much rarer
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