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Research in rodent models has characterized MC4R-mediated effects on food intake suppression, energy expenditure, and autonomic outflow, establishing MT-2 as a widely used pharmacological tool for probing central melanocortin circuitry (Huszar et al., Cell, 1997
The decreased dosage plan is not necessary, but it is highly recommended
Safi C, Zebib B, Merah O, Pontalier PY, Vaca-Garcia C
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