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It requires daily injections because its half-life is only 13 hours, reaching steady state within two to three days
For lyophilized powder at room temperature, the timeline is more forgiving than you might expect
Reduced metabolic rate is a primary consideration
Perhaps more concerning is that 11 to 50% of total weight loss in GLP-1 RA users is attributed to loss of lean body mass, which may detrimentally include loss of skeletal muscle 26 , potentially negatively impacting metabolism, strength and long-term health
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