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Curcumin inhibits the AKT/NF-B signaling via CpG demethylation of the promoter and restoration of NEP in the N2a cell line

These findings highlight the potential of KD in managing PD, warranting further exploration of its long-term effects

That is one of the reasons, as the NICE guideline says, that we need to adjust treatment to the patients symptoms, not do a blood test or prescribe a one-size-fits-all dose