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Repeated freeze-thaw cycles can degrade any peptide, including GHK-Cu, by causing structural stress

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Kang and colleagues were inspired to conduct their simulations after viewing images of Jupiter captured by the Juno spacecraft, which has been orbiting the solar system's largest planet since 2016, and by images of Saturn delivered by Cassini over 13 years of observations before it was deliberately plunged into the ringed planet at the end of its mission in 2017

Both compounds have been shown to ablate senescent cells in a ROS (reactive oxygen species)-independent manner and are able to synergize with other senolytic compounds like navitoclax (ABT-263) (56, 58, 59)