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Research shows that both naturally aged wildtype mice and fast-aging XpdTTD/TTD mice develop progressive kidney dysfunction characterized by elevated plasma urea and creatinine levels, established biomarkers of reduced glomerular filtration capacity

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Originally characterized by the Sikiric group at the University of Zagreb School of Medicine, BPC-157 is unusual among peptides for its reported oral activity attributed to its origin in gastric juice, which suggests evolutionary adaptation to the digestive environment

In addition, the increase in the phosphorylation of p38 MAPK was not statistically significant (Figure 6)