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Any reference to dosage should be understood only in a laboratory research context and should not be taken as medical advice
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During the initial screening of titles and abstracts, 894 articles were excluded due to irrelevance to the study objectives
Observed Heart Rate Changes: Increase of 5-10 beats per minute during treatment Peak increase around week 24, then gradual decline Persists but diminishes through week 68 Why This Happens: Sympathetic nervous system activation Increased metabolic rate from weight loss Direct effects on cardiac tissue Clinical Significance: Modest heart rate increases (5-10 bpm) don't appear harmful in clinical trials
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