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With a severe deficiency, it can honestly take months of maintenance shots before you feel completely better again

The injections can create problems in various body parts like the heart, lungs, skin, brain, and muscles

(Outlines contraindications for niacin therapy, including active peptic ulcer disease, active liver disease with elevated enzymes, hypersensitivity to niacin, and arterial bleeding, as well as monitoring recommendations for blood pressure, glucose, uric acid, etc., due to niacins systemic effects)

Sometimes pain comes down to technique - injecting too slowly or at the wrong angle can increase discomfort