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In the sensitivity analyses, the primary outcome analysis was repeated for the PP sample, defined as participants who followed the study protocol with full adherence, attending all study visits with no substantial interruptions in treatment as monitored from the drug dose diary
A body mass index (BMI) over 25 is considered overweight, and over 30 is obese. According to the WHO the rate of obesity worldwide doubled in adults and quadrupled in adolescents between 1990 and 2022
The handful of these nutrient-sensing mechanisms thus far identified have had a profound impact on human health
Pulmonary aspiration Pulmonary aspiration may occur when solid or liquid material enters the lungs or trachea
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