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Ocular and Psychiatric Safety Signals Retinopathy and neuropsychiatric outcomes have generated additional safety discussions

If headaches persist beyond the first week, check whether you are eating enough calories, as appetite suppression from increasing GLP-1 can lead to inadvertent calorie restriction that causes headaches

This peptide is derived from a naturally occurring protein in human gastric juice, Body Protection Compound (BPC), which helps protect and repair tissues

To model food restriction, the authors used semaglutide, a glucagon-like peptide-1 receptor (GLP1R) agonist that induces fasting-like metabolic responses