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To prevent side effects, these medications should be started at a low dose and increased over time
It is studied for its role in chemoattraction (pulling repair cells to a site of injury) and the modulation of Metalloproteinases (MMPs) to prevent excessive scarring
Interventions The GLP-1 RA semaglutide (0.5 mg followed by 1 mg) (Ozempyc, Novo Nordisk A/S Bagsvaerd, Denmark) or placebo will be administered once weekly as subcutaneous injections in the abdomen or thigh
For a broader comparison including newer options, see our semaglutide versus tirzepatide versus retatrutide analysis
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