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Naltrexone/bupropion (Contrave): Naltrexone works as an opioid receptor antagonist, which can reduce the rewarding effects of food and cravings, particularly for high-calorie, high-sugar foods
Suicidal ideation Interestingly, this warning appears in the prescribing information for Wegovy but not Ozempiceven though both contain semaglutide
GLP-1 is particularly relevant in conditions such as type 2 diabetes and obesity, both of which are associated with impaired glucose regulation
Additionally, native GLP-1 increases endothelial function and vasodilation in both diabetic and non-diabetic patients, regardless of alterations in insulin sensitivity
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