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Symptoms of gallbladder problems may include pain in your upper stomach (abdomen), fever, yellowing of the skin or eyes (jaundice), and clay-colored stools. Indeed, some research indicates individuals with type 2 diabetes taking tirzepatide are at greater risk of developing gallbladder or biliary disease

That's why doctors stress drinking fluids early and often, not just when you feel thirsty

Related Treatments TB-500 Therapy Thymosin Beta-4 fragment for systemic tissue repair, inflammation reduction, and accelerated recovery

Common gastrointestinal effects (Phase 2 NEJM) Retatrutide GI side effects at 12 mg in the Phase 2 NEJM trial Effect Nausea Rate at 12 mg Up to 25% Effect Diarrhea Rate at 12 mg Up to 23% Effect Vomiting Rate at 12 mg Up to 26% Effect Constipation Rate at 12 mg Up to 16% GI symptoms were most common during dose escalation and were usually mild to moderate