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AOD-9604 progressed through six human clinical trials with more than 900 participants but failed to reach statistical significance in its Phase IIb obesity endpoint, and Metabolic Pharmaceuticals terminated development in 2007

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It's worth being realistic here: Topically applied Hydrolyzed Collagen conditions the upper layers of skin rather than rebuilding the structural collagen deep in your dermis (the wrinkle-and-firmness benefits people associate with Collagen mostly come from oral supplements in studies, not topicals)

Patients considering this therapy should consult with their healthcare provider to ensure it is appropriate for their condition and to discuss potential benefits and risks