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Serious Risks: Prescribing information for GLP-1 medications includes boxed warnings about: Thyroid C-cell tumors (observed in rodent studies) Pancreatitis risk Gallbladder disease Kidney problems Adherence Factors: According to experts quoted in coverage of the FDA approval, real-world adherence may differ from clinical trial conditions

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This finding ran counter to the researchers initial expectations that individuals at a higher weight would be most stigmatized, and suggests that medication-assisted weight loss may be perceived by some as socially undesirable or morally questionable, despite its medical effectiveness