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Body surface area scaling, which is commonly used to extrapolate rodent doses to larger species, has known limitations for peptides specifically, because peptides are subject to enzymatic degradation in ways that small molecules aren't
Glutathione concentrations in the brain decline with age, and this decline has been associated with increased vulnerability to neurodegenerative processes
For instance, women tend to eat less as they approach ovulation, and find it harder to resist cravings during perimenopause, when estrogen and other sex hormones are in flux
Then came Thanksgiving night...I had 3.5 glasses of champagne/wine over the course of the day and night (12 hours), which is more than my typical weekly consumption
