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If you have severe symptoms, stop semaglutide and contact your prescriber
The visible and subjective changes at weeks 3 to 4 are driven more by improved sleep architecture than by significant IGF-1 elevation
Several medications use similar eligibility guidelines for chronic weight management
Occurred in 8.8% of participants on 9 mg and 20.9% on 12 mg, compared to 0.7% on placebo Dose-dependent (higher dose, higher risk) Generally described as mild Rarely led to discontinuation Why this matters: Dysesthesia was not reported in the Phase 2 trial
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