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The GM17 media control and the PMA positive control had GLP-1 levels of 565 188 pM and 1767 120 pM GLP-1, respectively, indicating a 56 fold increase in activity by JA1 and JA8 over the medium control

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Inhibiting GLUD1/RSK2 has been shown to enhance the infiltration of CD8 + T cells and increase IFN- levels within tumors, indicating the critical role of GLUD1 in shaping the immune microenvironment in specific cancer subtypes [207]

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doi:10.1016/j.bcp.2016.08.015

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