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Methylcobalamin B12 is also indicated in those with pernicious anemia, diabetes, neuropathy, heart disease, circadian rhythm sleep disorders, memory loss, depression, fatigue, AIDS, inflammatory bowel disease (IBD), Lyme disease, osteoporosis, tendonitis, psychiatric disorders, Alzheimers disease, liver and kidney disease, and asthma

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If you already take a daily multivitamin, it delivers more than enough to cover the average body's daily need

For example, PLP is required for the synthesis of neurotransmitters such as GABA and serotonin, for heme biosynthesis (through -amino levulinate synthase in red blood cell production), and for amino acid transformations