When NNMT activity is reduced, less nicotinamide is methylated and wasted, allowing NAD pools to remain higher
Some doctors are paid as little as $500 a month and are rarely present, prompting one surgeon to call it the worst-kept secret in this industry and the Wild West. Lawsuits detail burns, blindness, and disfigurement from improperly performed laser and filler procedures, and a 2025 study found many medical directors lacked required board certifications or supervised multiple spas in violation of state rules
However, these may not be safe for everyone
Lau, J., Bloch, P., Schaffer, L., Pettersson, I., Spetzler, J., Kofoed, J., Madsen, K., Knudsen, L.B., McGuire, J., Steensgaard, D.B., Strauss, H.M., Gram, D.X., Knudsen, S.M., Nielsen, F.S., Thygesen, P., Reedtz-Runge, S., Kruse, T