Remarkably, however, it is still not understood why the glucagon response is deficient or even absent in individuals with type 1 diabetes (and long-standing type 2 diabetes [58]), where this deficient response appears to be independent of the presence or absence of autonomic neuropathy [59]
545 In the development of drugs for UC, in addition to continuing to optimize existing drug targets and therapeutic strategies, we should also focus on the development of drugs with novel mechanisms of action
Wegovy has been approved by the HSA for chronic weight management since 2023, and from late 2025 clinics and telehealth providers have been prescribing it and tirzepatide at scale
Notably, a modest amount of weight loss (5-10% of your body weight) with intermittent fasting can have significant health benefits, including lower blood pressure, better blood sugar levels, and reduced blood cholesterol levels