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Clinical experience suggests that for many patients, gastrointestinal symptoms tend to improve with continued therapy as physiological adaptation occurs
A responsible medical discussion should include possible benefits, limitations, risks, alternatives, red flags, and a plan for monitoring progress
Moreover, recently, Kim et al., have demonstrated the deregulation of some carnitine-acylcarnitine metabolic pathway-associated genes, such as CPT1B, that results in an increased mortality in patients with muscle-invasive bladder cancer 42
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