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Patients typically begin to notice weight loss within the first few weeks of treatment, with progressive effects over several months as the dose is titrated upward
Injecting into lipohypertrophic tissue reduces drug absorption, creating unpredictable pharmacokinetics that undermine the very stability microdosing aims to achieve
[1] Simultaneously, it suppresses glucagon secretion from pancreatic alpha cells, which helps prevent the liver from releasing excess glucose into the bloodstream
Gutierrez-GrobeYChavez-TapiaNSanchez-ValleVGavilanes-EspinarJGPonciano-RodriguezGUribeMet al
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