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It means protocols become unreliable, results are inconsistent and dose-response cannot be properly evaluated
Firmer, smoother skin Peak Peak-renewal territory in the literature: firmness, skin texture and scalp / follicle endpoints are commonly assessed here
Finally, large-scale DNA methylome profiling of cells in different stages of development or cell cycle might provide us with a list of coding and/or noncoding regions that seem to remain stably methylated (such as inactive X-chromosome and imprinted regions) and a list of genomic regions showing dynamic changes in their methylation pattern
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