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When considering Wegovy for weight loss in non-diabetics, its essential to understand how it compares to other medications in terms of mechanism, efficacy, and usage
The co-primary endpoints were percent change from baseline in body weight and proportion of patients achieving 5% additional weight loss (i.e., beyond that already achieved by the lifestyle intervention)
Given the numerically lower acceptance bias parameter in the type-2 diabetes group on semaglutide, these findings align with the idea that altered effort-based decision-making tracks with metabolic ill-health in a dimensional manner, as suggested by results discussed above
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