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References 1 CaronBHonapSPeyrin-BirouletL
Currently, prodrugs under research comprise TLK286, purine analogs, 77 sulfonamides, 78 and brostallicin
Certainty of evidence At the class-level, certainty of evidence was highest for the GLP-1RA class compared with placebo, with high certainty observed for CV mortality, all-cause mortality, and non-fatal stroke, and moderate certainty for MACE and non-fatal MI, secondary to heterogeneity or imprecision for certain outcomes (Supplementary Table S25)
GLP-1RAs may be the game changers for CKD in the next decades
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