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Three tissues/organs are affected in PCD: cardiac muscle which leads to progressive cardiomyopathy

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This mechanism represents a control of the influx of fatty acyl units into mitochondria in response to the intra-mitochondrial acetyl-CoA level, in addition to the finely regulated mechanism of CPT1 by malonyl-CoA

In addition, juglone induced ferritin phagocytosis to increase Fe 2+ , which inhibited the migration and invasion of endometrial carcinoma Ishikawa cells (Zhang et al., 2021)