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Non-native disulfide bonds are often formed between incorrect cysteine residues, and thus the cell has dedicated a family of oxidoreductases that are thought to isomerize non-native bonds
Red flags include: no lot-specific COA available, purity stated as a range rather than a measured value, no endotoxin or bioburden testing, website health claims implying human use, no verifiable third-party testing lab named on the COA, and pricing far below the synthesis cost for a complex 83-amino-acid peptide
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10.1016/j.cell.2022.06.003 59 WanS.-S.ChengQ.ZengX.ZhangX.-Z
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