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In untrained individuals, the cerebral circulation exhibits greater sensitivity to reductions (than increases) in mean arterial pressure, demonstrating a greater change in MCAv (and assumingly CBF) during a hypotensive stimulus compared to a hypertensive stimulus (Roy et al., 2022

Helps Manage Blood Sugar Levels Blood sugar spikes and crashes are a major driver of food cravings, especially for sugary snacks and refined carbohydrates

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However, the reduced caloric and fluid intake that GLP-1 appetite suppression causes can affect supply if intake drops too low