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2.4.2 Hydroxysafflor yellow A (HSYA) HSYA extracted from the flower of Carthamus tinctorius L., as a chalcone glycoside, can effectively increase the activities of antioxidant enzyme and reduce oxidative stress mediated damage, which was extensively used in traditional Chinese medicine to treat cirrhosis
In this study, we found that LOsG treatment elevated the protein levels of TGF1, p-SMAD3, and SMAD4 in rat pancreas
For example, in a randomized double-blinded trial, NAC (600mg twice per day) given with L-arginine (1200mg per day) to diabetic men with hypertension lowered blood pressure, and improved many markers of endothelial function and inflammation, including C-reactive protein, fibrinogen, and LDL-cholesterol
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