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Loading and maintenance phases Some peptides benefit from loading phases with higher initial doses, followed by reduced maintenance dosing

Krivic, A., Majerovic, M., Jelic, I., Seiwerth, S., & Sikiric, P

L., Fragala, M

ii) Primary culture of satellite cells with 5 ng/ml HGF, which received only the LASSS pre-treatment (at 1:8000, without peroxynitrite treatment), exhibited a cell-proliferation activity (evaluated by mRNA expression levels of MyoD and its counter-regulatory factor myogenin at 48-h and 72-h time-points) comparable to that of the positive control culture treated with 5 ng/ml control HGF without LASSS (just with the solvent