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For the behavioral experiments of SPF-Sham, ABX-Sham and ABX-SDV, mice were tested for OFT at 11 weeks of age, EPM at 12 weeks of age, and motor function test (wire hanging test, ledge test, and hindlimb clasping test) at 13 weeks of age
The process varies by state
H.FrydlandM.Winther-JensenM.et al (2018)
less than 1% for cagrilintide) Metabolite excretion predominance with degraded peptides comprising the majority of eliminated material No dose adjustment required in hepatic impairment
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