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Future clinical trials evaluating IL-4R inhibitors in OvCa could provide critical insights into their efficacy in reversing macrophage-mediated immunosuppression and enhancing response rates to immune checkpoint inhibitors (72)
For instance, food proteininduced enterocolitis syndrome (FPIES) is a life-threatening condition occurring during infancy manifested by large volume diarrhea, acidosis, and shock as a result of an allergic reaction to common food proteins such as milk and soy
This dual nature has contributed to theoretical concerns
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