Even some meat eaters dont absorb it very well (4, Unlike other vitamins, the absorption of vitamin B12 depends on a protein produced in your stomach, called intrinsic factor
These extremely rare side effects include: Reactive thrombocytosis during the first week of use in megaloblastic anaemia Hypersensitivity reactions including: rash, itching, exanthema, antibodies to HYDR0XOCOBALAMIN-transcobalamin II Anaphylaxis Hypokalaemia Headache, paraesthesia, tremor Irregular heartbeat (arrhythmias secondary to hypokalaemia) Nausea Vomiting Diarrhoea Fever, chills, hot flushes, dizziness, malaise, pain and / or swelling at the injection site Acne Abnormal colouration of the urine (chromaturia) B12 injections work quickly
For a patient whose clinical question is "how do I reduce visceral fat under medical supervision," the honest answer in 2026 is that Tesamorelin has stronger evidence, particularly in metabolic and HIV-associated visceral adiposity
Absorbed vitamin B 12 is transported via specific B 12 binding proteins, transcobalamin I and II to the various tissues