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Upon initiating therapy, the endocrinologist ensures appropriate dose titration to minimise GI side effects, provides education on injection technique and timing, and establishes therapeutic goals, such as glycaemic control, weight reduction, and improvement in cardiometabolic risk
Not every patient needs the maximum dose to achieve their goals, and pushing dose escalation faster than the patient's tolerance warrants produces unnecessary side effects and dropout
Many initial denials are overturned
Long, needle-like carbon nanotubes and asbestos activate the NLRP3 inflammasome through a similar mechanism
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