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The evidence base demonstrates both efficacy and safety across diverse patient populations
Furthermore, it has been reported that tenocytes with IGF-1 (10, 50, and 200 ng/mL) displayed the increased expression of tenocyte-associated structural protein genes for type I collagen (COL1A2), and type III collagen (COL3A1), but this effect is not dose-dependent and highest values were achieved at 50 ng/mL (Caliari and Harley, 2013)
In clinical trials, tirzepatide helped patients lose an average of 20.9% of their body weight over 72 weeks
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