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How B12 injections works

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doi:10.1007/s40262-016-0501-5 Dorr RT, Ertl G, Levine N, et al

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When activity is impaired, the opposite can occur

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3e, in both A375 and B16F10 cells, only DeTYR-3 formed from the TYR-catalyzed VH032-Azi3 + Alk-TIn + SA group could successfully form a ternary complex between TYR, DeTYR-3, and VHL, as evidenced by the detected TYR in the final precipitated protein samples pulled down by anti-VHL antibodies in VH032-Azi3 + Alk-TIn + SA group rather than DMSO and epi-VH032-Azi3 + Alk-TIn + SA control groups

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