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Dose-dependent efficacy for more pronounced effects
When a patient is already symptomatic, the clinician's job shifts from assessing the peptide's therapeutic potential to identifying which contaminant class is driving harm and selecting the correct pharmacological countermeasure
Rather than acting as a dramatic skin-lightening treatment, the current evidence suggests GSH may support brighter, more even-looking skin as part of its broader role in protecting cells from oxidative stress
For GSH assay, cells were treated in Earles balanced salt solution (EBSS), supplemented with 25 mM glucose, 4 mM glutamine, 1 X MEM vitamin solution (Life technologies, CA, USA), 0.22% wt/vol NaHCO 3 , 1 mM sodium pyruvate, 0.2% BSA, 25 mM HEPES, 100 U/ml penicillin and 100 g/ml streptomycin in the presence or absence of 1 X MEM amino acid solution (Gibco, CA, USA) with or without 100 M cystine
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