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IGF-1 is a primary mediator of growth hormone (GH), with growth-promoting effects on most cells and tissues including skeletal muscle, cartilage, bone, liver, kidney, nerve, skin, hematopoietic, and lung [1]
Many patients suffering from a B12 deficiency visit their GP complaining of tiredness and fatigue
GH-GHR initiation of STAT5b can promote the expression of local IGF which then acts in an autocrine manner to stimulate PI3K/Akt signaling and enhances FSH-FSHR activities (Figure 2)
It's sold as a research compound or food supplement, depending on the vendor's classification
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