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In concordance with this regulatory scheme, ablating IGF-IR genes in cultured chondrocytes inhibits the ability of high [Ca 2+ ] e (by 50%) to enhance terminal differentiation and matrix mineralization, supporting a role for IGF-I/IGF-IR signaling in mediating CaSR-induced chondrocyte differentiation (Figure 1)
Glutathione Assay Kit Features Measure total, oxidized (GSSG) and reduced (GSH) glutathione colorimetrically Assay Range: 0.1-2.5 M for GSSG and for GSH it would be 0.2-5 M Plated based, colorimetric measurement at 405-415nm End-point and kinetic methods 225 and 450 assay sizes available The assay is designed to measure glutathione in wide range of samples such as plasma, blood, serum, urine, cultured cells, tissue etc
LRP1 regulates peroxisome biogenesis and cholesterol homeostasis in oligodendrocytes and is required for proper CNS myelin development and repair
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