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It also plays a key role in calcium absorption and immune function
For metformin users, the MHRA recommends periodic monitoring, especially in those with symptoms suggestive of B12 deficiency
A randomized controlled trial by Miller, Wagner, and colleagues published in the Archives of Facial Plastic Surgery in 2006 evaluated topical copper tripeptide complex on CO2 laser-resurfaced skin in 13 patients and found no statistically significant differences between groups for resolution of erythema, wrinkles, or overall skin quality on objective assessment, although subjective patient-reported skin quality favored the GHK-Cu side (p = 0.04)
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