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As muscle cells become less responsive to insulin, glucose redirects toward fat storage rather than energy production
10.1001/archinternmed.2010.130 311 StasonW
In addition to genetic factors, PE has been associated with a family history of hypertension, cardiovascular disease, renal disease, diabetes, obesity, unhealthy dietary patterns, advanced maternal age (aged 35 years), nulliparity, and multiple gestation 3,11
Clinical trial durations: Most obesity studies used daily dosing for 12 weeks Wellness clinic use: Often structured in 8-week cycles, followed by reassessment before continuing
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