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Furthermore, pramlintide causes only modest mean weight loss of 1.6 kg and HbA1c reduction of 0.34Percentage compared with placebo [4]
For instance, AMG 337, a potential and highly selective small molecule Met kinase inhibitor, significantly decreases tumor growth of Met-high-expression and Met-amplified HCC cell lines in in vitro and in vivo trials (Du et al., 2016)
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