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The strongest preclinical evidence supports BPC-157 use for tendon and ligament repair, gut-lining integrity in NSAID-related damage, and inflammation reduction in musculoskeletal tissues
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Obesity itself promotes chronic low-grade inflammation through adipose tissue secretion of inflammatory cytokines
44, 77 Methymalonic acid, a metabolite of PPA, results in abnormal mitochondrial morphology, 78 tissue specific ETC dysfunction, 79 inhibition of the complex I and II function when interacting with complex III in the brain 80 and reductions in reduced glutathione, 78 similar to the patient cohort presented and the PPA animal model
